Leucocyte and macrophage recruitment in IBD

Status: Ongoing

Our team actively contributes to the advancement of research within the Adult Inflammatory Bowel Disease (IBD) INCEPTION Cohort, the largest initiative of its kind in the UK. Our focus lies in the comprehensive immunological analysis of patient materials derived from the cohort. This involves employing cutting-edge techniques such as single-cell RNA sequencing, flow cytometry, and CYTOF platforms to conduct immune cell phenotyping. Additionally, we aim to identify and characterise inflammatory biomarkers, with the goal of developing unique and novel signature profiles specific to Crohn’s disease and ulcerative colitis.