Diet and physical activity in pregnancy to prevent gestational diabetes
Research theme
Women’s metabolic healthPeople involved
Women's Metabolic Health Theme Lead
Status: Ongoing
Women with gestational diabetes, a condition with high blood sugars diagnosed for the first time in pregnancy, are at increased risk of complications in pregnancy and type 2 diabetes after delivery. Diet and physical activity interventions have the potential to prevent gestational diabetes. However, variations in the population, intervention, and outcome definitions in primary trials have limited the translation of evidence on lifestyle interventions into practice. Individual participant data (IPD) meta-analysis can address these limitations.
Project aims
Using IPD meta-analysis, this study aims to determine whether diet and physical activity based interventions prevent gestational diabetes and its complications, if the benefits vary according to the maternal characteristics and the type of intervention, and whether they are cost-effective, by updating and expanding the NIHR funded i-WIP (International Weight Management in Pregnancy) database.
Research projects
The Duchess phenome study
Overproduction of male hormones, androgen excess, is common in children before they enter…
New therapeutic intervention for persons with adrenal…
This experimental medicine study focuses on a novel therapeutic intervention for persons with…
Sleep and mental health during pregnancy
In this study, we explore sleep patterns in mothers during pregnancy and also…